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  • 發布時間:2020-04-29 21:38 原文鏈接: ImmuneChem產品在蛋白質翻譯后生物修飾最新動向

    最新Nature刊登的科技文獻指出: 通過比較Sigma,SantaCruz的同類產品, 只有ImmuneChem的抗生物素抗體Agarose填料達到PTM蛋白質組學質譜分析應用的質量。蛋白質翻譯后生物修飾是新的PTM研究領域。 抗生物素抗體Agarose填料也是非破壞性(Non-invasive)純化Biotin-tag重組蛋白的重要填料, 可不必用蛋白變性溶液而直接用游離生物素洗脫。 比傳統Avidin, Streptavidin Agarose要理想。


    ImmuneChem Biotin Antibody Agarose produced the best results in research article published in:

     Nature Methods
    Volume 14, Issue 12, 16 October 2017, Pages 1167–1170


    The binding affinity of anti-biotin antibodies could improve the elution of biotinylated peptides. This table shows the difference in the # of unique peptides when samples are biotinylated.

     

    Biotin antibody compared to non-biotin samples

     

     

    Immunechem’s Biotin Antibody Agarose (ICP0615) yielded the highest number of biotinylated peptides

    compared to Sigma-Aldrich and Santa Cruz.

     For more details, please refer to:
    Nature Methods

    Volume 14, Issue 12, 16 October 2017, Pages 1167–1170


     



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