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  • 發布時間:2022-08-09 08:51 原文鏈接: CDH2基因編碼功能及結構描述

    這個基因編碼一個典型的鈣粘蛋白和鈣粘蛋白超家族的成員。選擇性剪接導致多個轉錄變體,其中至少一個編碼前蛋白,經蛋白質水解處理后生成鈣依賴性細胞粘附分子和糖蛋白。這種蛋白質在左右不對稱的建立、神經系統的發育以及軟骨和骨的形成中起作用。[由RefSeq提供,2015年11月]

    This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]

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