該基因編碼一種參與花生四烯酸轉化為12R-羥基二十碳四烯酸的酶。該基因突變與非大皰性先天性魚鱗病樣紅皮病有關。[由RefSeq提供，2015年9月]
This gene encodes an enzyme involved in the conversion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. [provided by RefSeq, Sep 2015]