這個基因編碼激活素A型IB受體。激活素是二聚體生長和分化因子，屬于結構相關信號蛋白轉化生長因子β（tgfβ）超家族。激活素通過受體絲氨酸激酶的異聚復合物發出信號，該異聚復合物至少包括兩個I型和兩個II型受體。這種蛋白質是一種I型受體，對信號傳導至關重要。這個基因的突變與垂體瘤有關。交替剪接導致多個轉錄變體。[由RefSeq提供，2010年6月]
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]